Pediatric Grand Rounds (CME): Ureteroscopy Versus Shockwave Lithotripsy to Remove Kidney and Ureteral Stones in Children and Adolescents: Results from the PKIDS Trial

Ureteroscopy Versus Shockwave Lithotripsy to Remove Kidney and Ureteral Stones in Children and Adolescents: Results from the PKIDS Trial

SPEAKER
Gregory Tasian MD, MSc, MSCE
Associate Professor of Surgery and Epidemiology,
University of Pennsylvania Perelman School of Medicine

SESSION DESCRIPTION
The Pediatric KIDney Stone (PKIDS) Care Improvement Network was established to strengthen the evidence base supporting the management of children with nephrolithiasis. The PKIDS study (NCT04285658) was an investigator-initiated, prospective cohort study embedded in the clinical care of children and adolescents undergoing kidney stone surgery between March 16, 2020, and July 31, 2023, at 31 medical centers in 22 states and one Canadian province that participate in the PKIDS Network. The PKIDS study was designed to answer the question whether ureteroscopy or shockwave lithotripsy a more effective surgery to remove kidney stones in children and adolescents. stone clearance was 71% for ureteroscopy as compared to 68% in the shockwave lithotripsy group, a difference that was not statistically significant. Ureteroscopy resulted in significantly more pain interference, urinary symptoms, and missed school one week after surgery compared to shockwave lithotripsy. Among children and adolescents with kidney and ureteral stones, shockwave lithotripsy resulted in similar stone clearance and better lived experiences than ureteroscopy, raising questions about current clinical practice wherein most children and adolescents with kidney stones undergo ureteroscopy.

EDUCATION GOALS

• To demonstrate the importance of of patient-centered outcomes research in urologic disease.
• Understand the clinical effectiveness and impact on lived experiences of ureteroscopy versus shockwave lithotripsy in children and adolescents with kidney stones.
• Demonstrate the discordance between evidence and clinical practice.

LOCATION (in-person)
Center for Academic Medicine
Grand Rounds Room
453 Quarry Road, 
Palo Alto, CA 94304

ZOOM INFORMATION
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